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← Longevity Science · Preclinical research · 2021
Researchers reported increases in neural stem cell measures and dendrite length in cell experiments, and improved object-recognition memory in a mouse model.
Laboratory cells and a mouse model; not a clinical trial in pet dogs or cats.
What the researchers observed
The authors report increased neural stem cell measures and dendrite length in cell experiments, and changes in memory outcomes in treated mice.
How this connects to your routine
This paper provides mechanistic context. It does not validate a pet longevity score, lifespan extension or a disease-prevention claim for the six products.
Understanding the study
- Study design: Laboratory cell and mouse experiments
- Participants or model: Cultured cortical cells and 5XFAD mice; mouse feeding groups of 4–6
- Preparation: Horse placental extract JBP-F-02.
What this study cannot tell us
Cell and mouse findings do not establish a clinical benefit in dogs, cats or people. The mouse groups were small, and the research preparation and experimental conditions may differ from retail products.
Read the original research
Horse Placental Extract Enhances Neurogenesis in the Presence of Amyloid β
de Toledo, Nomoto, Hirano and Tohda
Nutrients · 13:1672 · 2021
DOI: 10.3390/nu13051672 ↗
Read full paper ↗ · Publisher or repository record ↗
Research relationships
Several authors are affiliated with Japan Bio Products, which supplied the extract.
Explore the everyday concerns
Back to the reading library · Compare our placenta collection
Research findings depend on the preparation, species and study design. These summaries provide context for informed conversations with your veterinarian; research doses do not replace product label directions.