Rooted in Japanese placental research
Japanese
Longevity Science.
Exploring vitality and healthy ageing.
For the everyday moments you share.
From Japan. With a wider perspective.
Japanese placental research meets the questions you have about your companion’s daily life.
Explore veterinary observations and laboratory studies from Japan and beyond, through movement, appetite, skin health and changing needs with age.
The research at a glance
Observations worth exploring.
A selected library of veterinary and laboratory research.
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The reading library
16
Research publications
12 canine & feline reports
4 laboratory publications -
Across this selected library
190
Dog & cat enrolments reported
188 dogs · 2 cats
Summed across sources, including comparison groups. -
Across this selected library
100%
Publications with favourable observations
16 of 16 publications report at least one.
Not a product success or safety rate.
How these figures are counted
Figures describe this selected library, including different placenta sources and study designs. Participant counts are summed across canine and feline publications, not verified unique animals. Laboratory mice and cultured cells are excluded from the dog and cat total. Duplicate copies of the same paper count once.
What have you noticed?
Choose a concern to explore
Vitality Enhancement
More interest in daily life and meals
You know their usual enthusiasm. A quieter greeting or less interest in meals can make you wonder what has changed.
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2026
Canine observationsMore vitality and interest in meals
Uncontrolled exploratory study in senior dogs; owner-rated outcomes, not established efficacy.
Owners reported improved vitality and appetite scores over 28 days in senior dogs receiving equine placental extract. These everyday ratings are the focus of this reading.
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2023
Case reportsLess exhaustion during an older dog’s care
One clinical case with concurrent treatment; it does not establish an energy benefit in healthy pets.
An older dog with suspected anaemia showed reduced exhaustion after equine placental extract was added to prescribed treatment. Here, the observation is about energy during illness.
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2026
Case reportsRenewed interest in meals during liver care
One older cat receiving combined care; the extract’s individual contribution to appetite is unknown.
A cat’s appetite returned during care for liver disease that included equine placental extract, medicines and nutritional support. This reading focuses on the reported change at mealtimes.
Mobility & Comfort
Encouraging changes in movement and comfort
Taking longer to get moving, hanging back on walks or hesitating at steps can change the little routines you share.
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2022
Conference abstractImproved movement and comfort scores
Conference abstract; no control group, randomisation or blinding described.
Veterinarians reported improved pain and activity scores during four weeks of placental extract supplementation in dogs with impaired movement. This study looks directly at mobility and comfort.
Read our summary Read conference abstract (PDF) (opens in a new tab)
Skin & Coat Support
Hair regrowth and a healthier-looking coat
Changes in coverage, shedding or shine are often the first things you notice when stroking or grooming your companion.
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2023
Canine observationsHair regrowth and improved coat condition
Dogs with hair loss; no separate comparator group identified in the methods.
Dogs with non-specific hair loss showed improvements in hair regrowth, coat shine and hair fall during monthly assessments with equine placental extract supplementation.
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2025
Case reportsImproved coat coverage with combined nutrition
One dog receiving several supplements and skin care; placenta’s individual effect is unknown.
A case report describes improved coat coverage in a dog receiving equine placental extract together with taurine, B vitamins and other skin care. The findings relate to the combined routine.
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2023
Preclinical researchExploring the skin’s antioxidant responses
Extract applied directly to cultured human skin cells; not an oral pet supplementation trial.
In cultured human skin cells exposed to UVB, equine placental extract activated antioxidant signalling and lowered selected inflammatory markers. This offers laboratory context for skin research.
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2022
Preclinical researchSkin-cell ageing under oxidative stress
Cultured human cells, not a trial in dogs or cats. The findings do not establish slower ageing or protection from sun damage in pets.
Equine placental extract reduced the proportion of cells showing a senescence marker in cultured human skin fibroblasts exposed repeatedly to hydrogen peroxide or UVA.
Healthy Ageing
Understanding their changing needs with age
A slower pace, changes around meals or more unsettled nights can raise new questions about caring for your senior companion.
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2026
Canine observationsEncouraging changes in ageing-related assessments
Uncontrolled exploratory study in senior dogs; preliminary findings do not establish slower ageing or a longer lifespan.
Over 28 days, senior dogs receiving equine placental extract had lower composite ageing-assessment scores. This broader assessment of age-related changes offers a different perspective on the same study’s vitality and appetite findings.
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2026
Case reportsEncouraging changes in cognitive signs
Six dogs; owner-reported scores and no comparison group. Lower scores indicate fewer reported cognitive signs.
Five of six older dogs had lower scores on a cognitive-dysfunction questionnaire at day 49, after four weeks of equine placental extract supplementation. Lower scores indicate fewer reported cognitive signs.
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2022
Case reportsQuieter nights reported in senior dogs
Three dogs with cognitive dysfunction; uncontrolled cases, with other medicines used in some dogs.
Owners of three senior dogs with cognitive dysfunction reported that night barking stopped after equine placental extract was added to their care. This case report addresses one specific concern within later-life care: unsettled nights.
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2022
Conference abstractMovement and comfort in later life
Conference abstract; no control group, randomisation or blinding described.
A four-week study in older dogs with impaired movement reported improved veterinarian-rated pain and activity scores. Here, the findings relate to movement as one part of caring for a senior companion.
Read our summary Read conference abstract (PDF) (opens in a new tab)
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2023
Case reportsMaintaining condition through ongoing care
One dog with a suspected diagnosis and several treatments; not evidence of an anti-ageing effect or a reason to change medicines.
The anaemia case report follows an older dog’s physical condition and blood findings during combined treatment, including veterinarian-managed steroid reduction. Here, the focus is continuity of care as health needs become more complex.
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2022
Case reportsDigestive stability with complex care needs
One eight-year-old dog receiving other treatments; not a healthy-ageing or routine digestive-support trial.
A dog with protein-losing enteropathy had no reported recurrence of diarrhoea or abdominal fluid accumulation during a combined regimen including equine placental extract. This is a clinical example of managing ongoing care needs.
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2024
Case reportsPhysical condition during veterinary care
Two cases receiving eye-drop treatment; the supplement’s independent contribution cannot be isolated. This is not evidence of an eye treatment or an anti-ageing effect.
In two older dogs treated for corneal injuries, the report describes improved physical condition and eye healing after equine placental extract was added alongside ongoing eye drops. This is a clinical observation within veterinary care for older dogs.
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2025
Case reportsEye comfort in a geriatric cat’s care
One cat receiving multiple treatments. The title uses “cats”, but this report concerns a single patient.
A 19-year-old cat showed improved eye discomfort and corneal signs after equine placental extract was added to ophthalmic treatment. The case offers a feline perspective on comfort during complex later-life care.
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2026
Case reportsFollowing stability through recurrent illness
One cat receiving medicines and nutritional support; no conclusion about slowing ageing or treating liver disease with the extract alone.
The liver-care case follows a 14-year-old cat through recurrent illness, with improving blood markers and continued clinical stability during combined care. Here, the focus is follow-up and changing needs in later life.
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2026
Canine controlled trialCognitive scores with a different placenta source
Cow placenta, not Furrmacy equine placenta; these findings cannot be transferred to our equine placenta products.
In a six-month trial, older dogs receiving cow placenta extract had lower cognitive-behaviour questionnaire scores than dogs receiving placebo. This adds context from a different preparation.
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2021
Preclinical researchExploring ageing-related neural pathways
Laboratory cells and a mouse model; not a clinical trial in pet dogs or cats.
Cell and mouse experiments reported changes in neural stem cell measures, dendrite length and object-recognition memory. They provide a laboratory perspective on ageing-related biology, separate from observations in pet dogs.
Changes in appetite, movement, skin or night-time behaviour are useful to discuss with your veterinarian, especially when new or persistent.
From the ingredient to your routine
One ingredient to explore.
A format that fits.
Our Japanese-made placenta products use equine placental extract. Choose your format by your pet’s species, size and labelled serving directions.
Research findings depend on the preparation, species and study design. Cow placenta research is labelled separately and does not establish benefits for our equine placenta products.
Keep exploring
The reading library
Browse all source summaries, including additional clinical observations.
Vitality, appetite and ageing-related assessments in senior dogs
2026 · Canine observations
A 28-day exploratory study reported improved owner-rated vitality and appetite, alongside lower composite ageing-assessment scores, in senior dogs receiving equine placental extract.
Uncontrolled exploratory study in senior dogs; owner-rated outcomes, not established efficacy.
Night barking in senior dogs
2022 · Case reports
Owners reported reduced night barking after equine placental extract was added to the care of three senior dogs.
Three dogs with cognitive dysfunction; uncontrolled cases, with other medicines used in some dogs.
Mobility observations in older dogs
2022 · Conference abstract
Veterinarians reported improved pain and activity scores over four weeks in dogs receiving a placental extract supplement.
Conference abstract; no control group, randomisation or blinding described.
Read our summary Read conference abstract (PDF) (opens in a new tab)
Skin & coat observations in dogs
2023 · Canine observations
Researchers reported hair regrowth, improved coat shine and reduced hair fall during monthly assessments of dogs receiving equine placental extract.
Dogs with hair loss; no separate comparator group identified in the methods.
Corneal recovery: two clinical cases
2024 · Case reports
Two dogs received oral equine placental extract alongside ongoing eye-drop treatment, with subsequent clinical improvement.
Two clinical cases receiving eye drops; the supplement’s contribution cannot be isolated.
Coat condition & combined nutrition
2025 · Case reports
Coat coverage improved during a regimen combining equine placental extract, taurine and B vitamins.
One dog receiving several supplements and skin care; placenta’s individual effect is unknown.
Exploring cellular pathways in ageing
2021 · Preclinical research
Researchers reported increases in neural stem cell measures and dendrite length in cell experiments, and improved object-recognition memory in a mouse model.
Laboratory cells and a mouse model; not a clinical trial in pet dogs or cats.
Antioxidant pathways in skin cells
2023 · Preclinical research
Equine placental extract activated antioxidant signalling and lowered selected inflammatory markers in cultured skin cells exposed to UVB.
Extract applied directly to cultured human skin cells; not an oral pet supplementation trial.
Skin-cell ageing under oxidative stress
2022 · Preclinical research
Equine placental extract reduced the proportion of cells showing a senescence marker in cultured human skin fibroblasts exposed repeatedly to hydrogen peroxide or UVA.
Cultured human cells, not a trial in dogs or cats. The findings do not establish slower ageing or protection from sun damage in pets.
Cognitive observations in six older dogs
2026 · Case reports
Five of six older dogs had lower cognitive-dysfunction questionnaire scores at day 49, following four weeks of oral equine placental extract supplementation.
Six dogs; owner-reported scores and no comparison group. Lower scores indicate fewer reported cognitive signs.
Cow placenta extract and cognition in older dogs
2026 · Canine controlled trial
Dogs receiving cow placenta extract had lower cognitive-behaviour questionnaire scores than the placebo group after six months.
Cow placenta, not equine placenta. A different preparation from the ingredient in our collection.
Digestive stability during veterinary care
2022 · Case reports
A dog with protein-losing enteropathy had no reported recurrence of abdominal fluid accumulation or diarrhoea during a combined regimen that included equine placental extract.
One clinical case with prescribed medicines and other supplementation; not a study of routine digestive support.
Energy and condition during anaemia care
2023 · Case reports
The report describes reduced exhaustion and maintained physical condition after equine placental extract was added to an older dog’s ongoing care for suspected immune-mediated haemolytic anaemia.
One dog with suspected disease receiving prescribed treatment; not a trial of energy support in healthy pets.
Eye comfort during care of an older cat
2025 · Case reports
An older cat showed improvements in eye discomfort and several corneal signs after equine placental extract was added alongside ophthalmic treatment.
One cat receiving multiple treatments. The title uses “cats”, but this report concerns a single patient.
Appetite and stability during feline liver care
2026 · Case reports
An older cat’s appetite returned and liver blood markers improved during combined care that included oral equine placental extract.
One cat receiving medicines and nutritional support; not evidence of a general appetite benefit in healthy cats.
Kidney-injury pathways in a mouse model
2025 · Preclinical research
In mice with adenine-induced kidney injury, oral equine placental extract was associated with lower indoxyl sulfate levels and reduced measures of kidney tissue injury, fibrosis and inflammatory-cell accumulation.
A 14-day laboratory mouse study, not a clinical trial in dogs or cats. It does not establish a treatment or preventive benefit for pets with kidney disease.
A selected collection from the supplied placenta research, including studies with Furrmacy involvement. Each summary identifies the study design, preparation and research relationships. This collection is not a systematic review.
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